Publications and Patents

Lee, H., Wu, Z., Corbi-Verges, C., Mok, M., Kang, S., Liao, S., Zhang, Z., Garton, M. De Novo Crystallization Condition Prediction with Deep Learning, Machine Learning in Computational Biology, 2019

Garton M, Corbi-Verge C, Hu Y, Nim S, Tarasova N, Sherborne B, Kim PM. Rapid and accurate structure-based therapeutic peptide design using GPU accelerated thermodynamic integration. Proteins, 2018

Garton M, MacKinnon SS, Malevanets A, Wodak SJ. Interplay of self-association and conformational plasticity in regulating protein function. Philosophical Transactions of the Royal Society B, 2018

Garton M, Nim S, Stone TA, Wang KE, Deber CM, Kim PM. Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB. Proceedings of the National Academy of Sciences of the USA, 2018

Inventor(s): GARTON M. et al. In-silico method for designing a (D)-polypeptide ligand. U.S. Patent Application N° 62/614.641 filed on January 8, 2018.

Garton M, Sayadi M, Kim PM. A computational approach for designing D-proteins with non-canonical amino acid optimized binding affinity. PLoS One. 2017

Najafabadi HS, Garton M, Weirauch MT, Mnaimneh S, Yang A, Kim P, Hughes T. Structural basis for kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding. Genome Biology. 2017

Corbi-Verge C*, Garton M*, Nim S*, Kim PM. Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads. Annual Reviews of Pharmacology and Toxicology. 2016. *denotes co-authorship

Garton M, Najafabadi HS, Mnaimneh S, Schmitges FS, Hughes T, Kim P. A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity, Nucleic Acids Research. 2015

Najafabadi HS, Mnaimneh S, Schmitges FS, Garton M, Lam KM, Yang A, Albu M, Weirauch, Radovani E, Kim P, Greenblatt J, Frey BJ, Hughes T. C2H2 zinc fingers greatly expand the human regulatory lexicon, Nature Biotechnology. 2015

Garton M, Laugton C, A Comprehensive Model for the Recognition of Human Telomeres by TRF1, Journal of Molecular Biology. 2013

Wodak SJ, Garton M, Malevanets A, McKinnon S. Self-association prompts proteins for new function: The role of altered dynamic properties, Journal of Biomolecular Structure & Dynamics (conference paper). 2013

Garton M, Recognition and Manipulation of Telomeric Single and Double Stranded DNA by Shelterin Proteins. Thesis.

 

Twitter

Click to learn more about our twitter feed

Learn More
Michael Garton

This is some temporary information

Learn More
Taught courses

Coming in 2019!

Learn More