April L Mueller, Carles Corbi-Verge, David O Giganti, David M Ichikawa, Jeffrey M Spencer, Mark MacRae, Michael Garton, Philip M Kim, Marcus B Noyes. The geometric influence on the Cys2His2 zinc finger domain and functional plasticity. Nucleic Acids Research, 2020
Lee, H., Wu, Z., Corbi-Verges, C., Mok, M., Kang, S., Liao, S., Zhang, Z., Garton, M. De Novo Crystallization Condition Prediction with Deep Learning, Machine Learning in Computational Biology, 2019
Garton M, Corbi-Verge C, Hu Y, Nim S, Tarasova N, Sherborne B, Kim PM. Rapid and accurate structure-based therapeutic peptide design using GPU accelerated thermodynamic integration. Proteins, 2018
Garton M, MacKinnon SS, Malevanets A, Wodak SJ. Interplay of self-association and conformational plasticity in regulating protein function. Philosophical Transactions of the Royal Society B, 2018
Garton M, Nim S, Stone TA, Wang KE, Deber CM, Kim PM. Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB. Proceedings of the National Academy of Sciences of the USA, 2018
Inventor(s): GARTON M. et al. In-silico method for designing a (D)-polypeptide ligand. U.S. Patent Application N° 62/614.641 filed on January 8, 2018.
Garton M, Sayadi M, Kim PM. A computational approach for designing D-proteins with non-canonical amino acid optimized binding affinity. PLoS One. 2017
Najafabadi HS, Garton M, Weirauch MT, Mnaimneh S, Yang A, Kim P, Hughes T. Structural basis for kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding. Genome Biology. 2017
Corbi-Verge C*, Garton M*, Nim S*, Kim PM. Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads. Annual Reviews of Pharmacology and Toxicology. 2016. *denotes co-authorship
Garton M, Najafabadi HS, Mnaimneh S, Schmitges FS, Hughes T, Kim P. A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity, Nucleic Acids Research. 2015
Najafabadi HS, Mnaimneh S, Schmitges FS, Garton M, Lam KM, Yang A, Albu M, Weirauch, Radovani E, Kim P, Greenblatt J, Frey BJ, Hughes T. C2H2 zinc fingers greatly expand the human regulatory lexicon, Nature Biotechnology. 2015
Garton M, Laugton C, A Comprehensive Model for the Recognition of Human Telomeres by TRF1, Journal of Molecular Biology. 2013
Wodak SJ, Garton M, Malevanets A, McKinnon S. Self-association prompts proteins for new function: The role of altered dynamic properties, Journal of Biomolecular Structure & Dynamics (conference paper). 2013
Garton M, Recognition and Manipulation of Telomeric Single and Double Stranded DNA by Shelterin Proteins. Thesis.
Apply for job opportunities on our website.
Click on the button below to follow Garton Lab on Twitter.
De Novo Crystallization Condition Prediction with Deep Learning.
Chemical and Engineering News
Our invention reported in Chemical and Engineering News!